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Inhibitors of Metabolite Synthesis: How Sulfa Drugs Work

Instructions:

Choose an answer and hit 'next'. You will receive your score and answers at the end.

question 1 of 3

What does it mean if two drugs have synergistic effects?

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1. What is folic acid?

2. Why are sulfa drugs selectively toxic?

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About This Quiz & Worksheet

How do sulfa drugs work against bacteria and what other drug is taken with these antibiotics to maximize their effect? You will need to be familiar with the terms relating to these drugs and what they combat in order to successfully complete the questions in this quiz/worksheet combo.

Quiz & Worksheet Goals

In these assessments you'll be tested on:

  • What is meant by two drugs having synergistic effects
  • What folic acid is
  • Why sulfa drugs and trimethoprim are selectively toxic
  • How sulfa drugs inhibit the first enzyme in the bacterial folic acid pathway

Skills Practiced

This worksheet and quiz will allow you to test the following skills:

  • Critical thinking - apply relevant concepts to examine information about antibiotics in a different light
  • Interpreting information - verify that you can read information regarding how sulfa drugs and trimethoprim inhibit enzymes and interpret it correctly
  • Defining key concepts - ensure that you can accurately define main terms, such as synergism

Additional Learning

To learn more about these drugs, review the accompanying lesson called Inhibitors of Metabolite Synthesis: How Sulfa Drugs Work. This lesson covers the following objectives:

  • Define metabolism
  • Discuss the metabolism of bacteria
  • Relate what sulfa drugs are and how they work
  • Detail how sulfa drugs work with trimethoprin to inhibit folic acid enzymes needed for bacterial reproduction
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