About This Chapter
Below is a sample breakdown of the Genetic Mutations chapter into a 5-day school week. Based on the pace of your course, you may need to adapt the lesson plan to fit your needs.
|Day||Topics||Key Terms and Concepts Covered|
|Monday||Base substitutions||Characteristics of base substitutions, including transitions and transversions|
|Tuesday||Insertions and deletions||Point mutations causing the addition or subtraction of nucleotide bases|
|Wednesday||Effects of base substitutions||How missense, nonsense and silent mutations alter protein function|
|Thursday||Effects of insertions and deletions||How changes to gene length and shifts in the codon reading frame result in frameshift mutations|
|Friday||Mutagens||Chemical and physical agents increasing the likelihood of mutations; examples of advantageous mutations|
1. How Point Mutations, Insertions, and Deletions Affect DNA
What are genetic mutations? How do they affect our DNA? This lesson covers the basics of point mutations and provides simple examples of different mutation types.
2. Effects of Mutations on Protein Function: Missense, Nonsense, and Silent Mutations
How does a tiny point mutation change the way a protein works? What are the consequences of base substitutions? In this lesson, we'll use an imaginary creature to explore missense, nonsense and silent mutations.
3. Mutagens: How the Environment Affects Mutation Rates
What causes mutations to occur in living things? How do we avoid mutations? Are mutations always bad? Discover answers to these questions and more in this lesson on mutagens.
4. Effects of Frameshift Mutations: Definitions and Examples
What is a frameshift in genetic translation? How can a frameshift mutation change a protein? In this lesson, learn about the codon reading frame and how frameshift mutations cause serious problems for polypeptide formation.
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