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Ch 14: Principles of Immunology

About This Chapter

This chapter is all about key principles of immunology. The lessons inside focus on important terms to know as well as the functioning of systems and core immunological concepts. You'll find the lessons presented in an engaging format that allows you to test yourself with practice quizzes along the way.

Principles of Immunology - Chapter Summary

This chapter guides you through central principles in immunology by looking at the components that contribute to the immune system as well as related terms and biological concepts. You'll also see how the immune system works with other systems and elements of biological makeup. The dashboard feature can help you stay organized through this material, with quick views of your progress and recent studying activity. By the end of the chapter, you'll have given your knowledge a boost when it comes to:

  • The concept of immunity and the anatomical barricades setup by the immune system
  • Symptoms of inflammation and what causes it
  • The purpose served by granulocytes and the forms they come in
  • Components of the innate and nonspecific immune system
  • Function of the complement and lymphatic system
  • Forms of adaptive immunity
  • Differentiating between T and B cells
  • Classifying antibodies and understanding their structure and function
  • How autoimmune diseases and hypersensitivity can occur
  • Distinguishing between blood types

16 Lessons in Chapter 14: Principles of Immunology
What Is the Immune System? - Our Body's Defense Against Pathogens

1. What Is the Immune System? - Our Body's Defense Against Pathogens

In this lesson, you will be introduced to the immune system. You'll learn about the innate and adaptive immune system, Edward Jenner, haptens and immune tolerance.

The Anatomical Barriers of the Immune System

2. The Anatomical Barriers of the Immune System

This lesson will cover the major anatomical barriers to infection of the innate immune system. We'll explore skin flora, gut flora, gastric acid, lysozymes, and the mucociliary apparatus.

What Is Inflammation? - Definition, Causes & Symptoms

3. What Is Inflammation? - Definition, Causes & Symptoms

This lesson will cover the process of inflammation and what your body might do after a bee sting. We'll find out the five cardinal signs of inflammation as well as anaphylactic shock, histamine and cytokines in the process.

Granulocytes: Types and Functions

4. Granulocytes: Types and Functions

In this lesson, you will learn what a leukocyte, granulocyte, neutrophil, eosinophil, and basophil are. You'll also learn about the importance of phagocytosis and chemotaxis.

Macrophages, Killer Cells & Other Cells of the Innate Immune System

5. Macrophages, Killer Cells & Other Cells of the Innate Immune System

This lesson will teach you about certain white blood cells of the innate immune system. Namely, we'll learn about phagocytes, monocytes, macrophages, mast cells, and NK cells.

The Complement System: Definition and Function

6. The Complement System: Definition and Function

This lesson will cover something known as the complement system. We'll delve into the key functions of this system, including opsonization, chemotaxis, and the formation of membrane attack complexes.

What Is Adaptive Immunity? - Definition and Types

7. What Is Adaptive Immunity? - Definition and Types

This lesson will help you distinguish between several different types of immunity. This includes passive immunity, active immunity, naturally acquired immunity and artificially acquired immunity.

The Lymphatic System: Definition and Fundamental Components

8. The Lymphatic System: Definition and Fundamental Components

This lesson will cover something known as the lymphatic system. You'll learn about bone marrow, lymph, the thymus, lymph nodes, spleen, and much more as we explore this critical component of your immune system.

What are T Cells: Creation and Function

9. What are T Cells: Creation and Function

This lesson will teach about the birth, maturation, and importance of T cells. You'll learn about T lymphocytes, cytotoxic T cells, helper T cells, memory T cells, and more!

What Are B Cells? - Function and Types

10. What Are B Cells? - Function and Types

This lesson will focus in on the generalities of B-cells, such as their place of generation, maturation, and training, as well as some specific types of B-cells, such as plasma cells and memory cells.

The Humoral Immune Response: Definition and Features

11. The Humoral Immune Response: Definition and Features

This lesson will describe what humoral immunity is, how it is activated, what is produced, and why. Find out as we explore antigen presenting cells, MHC, T cells, B cells, plasma cells, and antibodies.

Antibodies: Their Important Structure

12. Antibodies: Their Important Structure

This lesson will cover the basic but important structural components and sites of an antibody as well as their function. This includes heavy chains, light chains, variable domains, constant domains, paratopes, and epitopes.

Antibodies: Their Function In the Immune System

13. Antibodies: Their Function In the Immune System

This lesson will delve into the three main ways by which antibodies function. We're going to discuss opsonization, agglutination and neutralization. We'll also learn what the Fc region is and why it's important.

The Five Classes of Antibodies

14. The Five Classes of Antibodies

This lesson will cover the five different classes, or isotypes, of antibodies. We will cover IgA, IgE, IgG, IgM, and IgD, as well as their basic structure and function.

Autoimmune Diseases and Hypersensitivity

15. Autoimmune Diseases and Hypersensitivity

This lesson will talk about what defines an autoimmune disease, a hypersensitivity reaction, and more. We'll also discuss Graves' disease and myasthenia gravis.

Blood Types: ABO System, Red Blood Cell Antigens & Blood Groups

16. Blood Types: ABO System, Red Blood Cell Antigens & Blood Groups

You are either blood type A, B, AB or O. But, did you know that your blood type is determined by microscopic antigens found on your red blood cells? In this lesson, you will learn about the different blood groups and why they do not mix.

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