Complete the following reaction and show a complete reaction mechanism for the transformation listed below.
Hydroxyl as a leaving group:.
In substitution reactions, the leaving group is replaced by a nucleophile. A hydroxyl group is a strong base and is a poor leaving group. The hydroxyl group is protonated to turn it into water which is a good leaving group.
Answer and Explanation:
Step 1: Protonation of the hydroxyl group
Step 2: Loss of water as a leaving group.
Step 3: Nucleophilic attack to give the alkyl chloride.
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from Organic & Inorganic Compounds Study GuideChapter 10 / Lesson 1