How do the thick (myosin) and thin (actin) filaments of the sarcomere interact to cause muscle contraction?
What Is the Sacromere:
Sarcomeres are the functional units of skeletal and cardiac muscle. Sarcomere are made up of bundles of proteins called myofibrils. Each myofibril is composed of lines of alternating thick and thin filaments, made of myosin and actin proteins respectfully.
Answer and Explanation:
During contraction the thick filaments of myosin bind to the actin filaments, allowing them to slide and shorten the length of the sarcomere. This cause muscle contraction. The thick filaments of myosin form cross bridges, binding with actin. In the presence of ATP, the motor protein action of myosin allows them to move towards the + end of actin. Since the actin molecules are attached to the Z disc in the sarcomere, this drives the actin towards the center, shortening the sarcomere and allowing for muscle contraction.
Learn more about this topic:
from UExcel Anatomy & Physiology: Study Guide & Test PrepChapter 14 / Lesson 4
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