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It has been stated that elevated homocysteine level accelerates thrombin formation. By what...

Question:

It has been stated that elevated homocysteine level accelerates thrombin formation. By what mechanism does this happen?

Thrombin:

Thrombin works with blood platelets and is very important for blood coagulation during bruises, cuts, surgeries, or injuries. Positive or negative feedback mechanisms strictly control the role of thrombin in the coagulation cascade.

Answer and Explanation: 1

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Homocysteine level increases thrombin formation by reducing the amount of thrombomodulin in the blood. Reduction in thrombomodulin levels increases...

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Blood Coagulation and Wound Healing

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Chapter 6 / Lesson 18
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After suffering a wound, the body does everything it can to promote blood clotting and, ultimately, wound healing. The general term hemostasis refers to the stoppage of bleeding, and it just one of the many factors, others being platelets and thromboxane A2, that are essential for proper wound healing. This lesson details the process of blood coagulation, from the clotting factors to the coagulation cascade.


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