Copyright

What is the major product of the reaction of 1-bromopropane with (1) NaCN, THF (2) EtMgBr, ether...

Question:

What is the major product of the reaction of 1-bromopropane with (1) NaCN, THF (2) EtMgBr, ether (3) dilute aqueous acid? 1. butanamine 2. 3-hexanone 3. butanoic acid 4. 2-hexanone 5. butanal

Grignard reactions

Alkyl halides react with nitriles via substitution. The alkyl nitrile formed can then react with a Grignard reagent and an aqueous acid to form a ketone.

Answer and Explanation: 1

Become a Study.com member to unlock this answer! Create your account

View this answer

First, CN displaces Br in 1-bromopropane via SN2 mechanism. The alkyl nitrile formed then reacts with the Grignard reagent, EtMgBr, and an aqueous...

See full answer below.


Learn more about this topic:

Loading...
Grignard Reaction with Alcohol, Ketone & Aldehyde

from

Chapter 10 / Lesson 28
47K

In this lesson, we'll learn about the Grignard reaction. We'll see how the reaction occurs with ketones and aldehydes, as well as how water and alcohols prevent this reaction from occurring.


Related to this Question

Explore our homework questions and answers library