Write the principal organic product formed in the following reaction: Ethyl acetoacetate with...

Question:

Write the principal organic product formed in the following reaction:

Ethyl acetoacetate with sodium ethoxide in ethanol, followed by 1-bromopentane

Reaction of enolate anion with alkyl halide:

The reaction between ethyl acetoacetate and sodium ethoxide will generate an enolate anion. The enolate anion will then react with 1-bromopentane via substitution reaction to afford the product.

Answer and Explanation:

The product of the reaction is given below. (All images are writer-generated)

The mechanism to explain formation of the product is given below.

...

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Learn more about this topic:

Aldol Addition: Mechanism & Reaction
Aldol Addition: Mechanism & Reaction

from Organic & Inorganic Compounds Study Guide

Chapter 12 / Lesson 1
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