Copyright

DNA Damage, Mutation, and Repair Chapter Exam

Exam Instructions:

Choose your answers to the questions and click 'Next' to see the next set of questions. You can skip questions if you would like and come back to them later with the yellow "Go To First Skipped Question" button. When you have completed the practice exam, a green submit button will appear. Click it to see your results. Good luck!

Page 1

Question 1 1. A mutation in DNA can affect the amino acid sequence because it affects the code found in _____.

Question 2 2. In DNA repair, what enzyme seals up broken parts of the DNA backbone?

Question 3 3. An example of a transversion mutation is _____.

Question 4 4. Based on the original sequence, ACTTGAC, which of the following answer choices includes a transition mutation?

Question 5 5. How does a frameshift mutation in the gene coding for the enzyme, hexosaminidase A, result in Tay-Sachs disease?

Page 2

Question 6 6. Which type of mutation does NOT change the overall function of the protein?

Question 7 7. Nucleotide excision repair recognises which type of faults in DNA?

Question 8 8. Which type of radiation is LEAST likely to cause mutations in cells deep inside of the body?

Question 9 9. _____ mutations result in a longer DNA strand.

Question 10 10. The eleventh amino acid of protein X should be serine, however due to a mutation it now has the amino acid alanine in that position. Which type of mutation could have caused this change?

Page 3

Question 11 11. The best term to describe the incorporation of a random mistake into the DNA sequence at a specific point is _____.

Question 12 12. An apyrimidinic or apurinic (AP) site forms in which type of DNA repair?

Question 13 13. What is a Holliday junction?

Question 14 14. Defective mismatch repair genes in humans have been linked with _____.

Question 15 15. How do sister chromatids differ from homologous chromosomes?

Page 4

Question 16 16. Which type of mutagen could be compared to an extra plate shoving itself into the middle of a stack of plates?

Question 17 17. Why do people try to protect their skin from ultraviolet radiation?

Question 18 18. What kind of DNA damage is repaired using Mismatch Repair?

Question 19 19. Which type of mutation results in an incomplete polypeptide because of an early stop signal?

Question 20 20. How does the mismatch repair machinery recognize an error in DNA?

Page 5

Question 21 21. Which enzyme checks DNA for errors?

Question 22 22. What is the correct order of the enzymes used in base excision repair?

Question 23 23. How can base analogs cause mutations?

Question 24 24. What is the relationship between a base and a nucleotide?

Question 25 25. When can a genetic mutation get passed down through successive generations?

Page 6

Question 26 26. A type of point mutation that alters the length of the DNA strand is _____.

Question 27 27. Which of these best describes the differences between ionizing and non-ionizing radiation?

Question 28 28. Which type of mutagen actually changes the chemical structure of certain nucleotides, causing them to mispair?

Question 29 29. Which type of double-strand break repair is the most likely to cause deletions or changes in the DNA sequence?

Question 30 30. A shift in the reading frame is usually caused by an insertion or a

DNA Damage, Mutation, and Repair Chapter Exam Instructions

Choose your answers to the questions and click 'Next' to see the next set of questions. You can skip questions if you would like and come back to them later with the yellow "Go To First Skipped Question" button. When you have completed the practice exam, a green submit button will appear. Click it to see your results. Good luck!

Biology 102: Basic Genetics  /  Science Courses
Support