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Holt McDougal Modern Biology Chapter 12: Inheritance Patterns and Human Genetics Chapter Exam

Exam Instructions:

Choose your answers to the questions and click 'Next' to see the next set of questions. You can skip questions if you would like and come back to them later with the "Go To First Skipped Question" button. When you have completed the practice exam, a green submit button will appear. Click it to see your results. Good luck!

Page 1

Question 1 1. Generally speaking, what are the odds that an autosomal dominant condition will be passed from an affected individual to their child?

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Question 2 2. Tay-Sachs disease is caused by:

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Question 3 3. Which of the following genetic techniques are used in human genetics?

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Question 4 4. Alleles A, B, C and D are linked on one chromosome, and alleles a, b, c and d are linked on the homolog. During meiosis, a crossover event occurs between genes A and B. Which of the following is an example of a chromatid that could be found in one of the resulting gametes?

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Question 5 5. How are genetic mutations related to genetic disorders?

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Page 2

Question 6 6. What is the most likely type of inheritance for the genetic condition shown in this pedigree?

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Question 7 7. Which of these is NOT a genetic birth defect:

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Question 8 8. The best term to describe the incorporation of a random mistake into the DNA sequence at a specific point is _____.

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Question 9 9. A type of point mutation that alters the length of the DNA strand is _____.

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Question 10 10. Which type of mutations can result in a frameshift?

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Question 11 11. What is the most likely type of inheritance for the genetic condition shown in this pedigree?

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Question 12 12. A diploid cell which has one copy of chromosome 16 would be _____.

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Question 13 13. If the diploid chromosome count in humans is 46, how many pairs of homologous chromosomes are there?

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Question 14 14.

Hemophilia is an X-linked recessive trait. Consider a cross between a woman who is a carrier and a man who suffers from hemophilia. Which of the following statements is/are true?

I. All sons of these parents will be a hemophiliac.

II. A son who suffers from hemophilia received the hemophilia allele from his mother.

III. Half of the daughters of this cross are predicted to be hemophiliacs.

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Question 15 15. At conception, your mother contributed a gene that encoded for the sickle hemoglobin (hemoglobin S), while your father contributed the same gene that encoded for normal hemoglobin (hemoglobin A). Which of the following denotes the DNA structures which carry these variants?

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Page 4

Question 16 16. This is a test that takes a sample of the placenta:

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Question 17 17. How would a shift in the reading frame likely alter the resulting protein?

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Question 18 18. Which of these does not influence the likelihood of developing birth defects?

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Question 19 19. Suppose you performed a cross with two flies that were heterozygous for purple eyes. The purple color allele is dominant to the black color allele. Which of the following possible results would NOT suggest that the organisms carried a recessive lethal allele?

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Question 20 20. How are autosomal genetic disorders different from sex-linked disorders?

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Question 21 21. The traits in polygenic inheritance can be described as _____.

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Question 22 22. Which of the following is an example of a sex-linked chromosomal error?

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Question 23 23. If this is a pedigree for a family with a history of hemophilia, which is a sex-linked condition, what do we know about the proband's mother?

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Question 24 24.

Genes A and B are located on the same chromosome arm in the following orientation: centromere, gene A, gene B, telomere. Which of the following recombinant chromatids could be produced by a crossover event between B genes in a heterozygote in which the dominant alleles are linked on one homolog and the recessive ones are linked on the other homolog?

I. A B

II. a B

III. A b

IV. a b

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Question 25 25. Which of these terms accurately describes Alzheimer's disease?

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Page 6

Question 26 26. What is a quantitative trait?

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Question 27 27. Which of the following statements about multifactorial traits is TRUE?

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Question 28 28. A shift in the reading frame is usually caused by an insertion or a

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Question 29 29. A criss-cross inheritance pattern is seen in what type of genetic inheritance?

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Question 30 30. How does a frameshift mutation in the gene coding for the enzyme, hexosaminidase A, result in Tay-Sachs disease?

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Holt McDougal Modern Biology Chapter 12: Inheritance Patterns and Human Genetics Chapter Exam Instructions

Choose your answers to the questions and click 'Next' to see the next set of questions. You can skip questions if you would like and come back to them later with the "Go To First Skipped Question" button. When you have completed the practice exam, a green submit button will appear. Click it to see your results. Good luck!

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