Adrenal Glands: Epinephrine, Norepinephrine & Stress Adaptation

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  • 0:05 Adrenal Medulla
  • 1:32 Epinephrine
  • 2:23 Norepinephrine
  • 3:32 Lesson Summary
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Lesson Transcript
Instructor: Rebecca Gillaspy

Dr. Gillaspy has taught health science at University of Phoenix and Ashford University and has a degree from Palmer College of Chiropractic.

The adrenal medulla is the central portion of the adrenal gland. In this lesson, you will learn about the two hormones secreted by the adrenal medulla - epinephrine and norepinephrine - and how they help you deal with short-term stressors.

Adrenal Medulla

The adrenal glands are found just above the kidneys.
Adrenal Glands Sit on Top of Kidneys

The adrenal glands sit on top of your kidneys. If you were to slice an adrenal gland in half, you would notice that it is more like two separate endocrine glands in one. The outer adrenal cortex secretes steroid hormones, and the central adrenal medulla is stimulated by the sympathetic nervous system to secrete catecholamines, which are hormones that help you deal with short-term stress. In this lesson, we will learn about the two catecholamines from the adrenal medulla - epinephrine and norepinephrine - and how they help you cope with everyday stressful situations.

It is not often that we see an endocrine gland stimulated by the nervous system. However, this is the case with the adrenal medulla. When you feel scared or physically threatened, your sympathetic nervous system springs into action to prepare you for fight or flight. For instance, if you are out for a peaceful hike in the woods and all of a sudden a bear appears, your sympathetic nervous system sends split-second impulses that help you make the decision to stay and fight or take flight. I recommend taking flight!

The sympathetic nervous system stimulates the adrenal medulla to secrete its hormones.
Sympathetic Nervous System Controls Adrenal Gland

One of the glands that the sympathetic nervous system stimulates is the adrenal medulla. Upon stimulation, the gland secretes its hormones into your bloodstream.


One of these hormones is epinephrine, which can be defined as a hormone secreted by the adrenal medulla in response to short-term stress. Epinephrine is also called adrenaline, and you may have heard of this term before. Typically, when we think of adrenaline, we think of the adrenaline rush we get when we act like a daredevil or do something risky or exciting.

This is a good way to recall the actions of epinephrine: When this hormone is secreted, it increases heart rate, blood pressure, cardiac output and blood glucose levels. These actions result in more blood to the muscles and more glucose available for quick energy. And, this makes us better prepared to deal with the stressful event that we are facing, whether it's a bear jumping out at us or riding a rollercoaster.

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