Antibiotic Resistant Bacteria Lesson Plan

Instructor: Adrianne Baron

Adrianne has a master's degree in cancer biology and has taught high school and college biology.

Antibiotic resistant bacteria are a problem the medical community is fighting. Your students will learn why this fight is important as they learn more about antibiotic resistant bacteria by reading and discussing a text lesson and completing a group and class activity.

Lesson Objectives

At the completion of this lesson, students will be able to:

  • Define antibiotic resistance
  • Identify examples of antibiotic resistant bacteria
  • Describe how bacteria become resistant to antibiotics


2 hours

Curriculum Standards


Cite specific textual evidence to support analysis of science and technical texts, attending to important distinctions the author makes and to any gaps or inconsistencies in the account.


Integrate and evaluate multiple sources of information presented in diverse formats and media (e.g., quantitative data, video, multimedia) in order to address a question or solve a problem.



  • Begin by explaining that there are some good bacteria that we depend on regularly and there are some very dangerous ones that cause diseases and death. Explain that we developed antibiotics as a way to get rid of the harmful bacteria, but just like we evolved to be able to get rid of them, they are evolving as well and that is creating a problem.
  • Tell them they are going to learn about the problem as they read the Antibiotic Resistant Bacteria: Evolution & Examples text lesson
  • Pass out the lesson and read it together as a class by having different students read each paragraph.
  • Stop for a discussion after reading the 'Bacteria and Antibiotics' section. Ask and discuss:
    • What is an antibiotic?
    • When are antibiotics prescribed by a doctor?
    • How much of the antibiotic should you take?
  • Continue reading through the 'Evolution of Resistant Bacteria' section, then ask and discuss:
    • What does antibiotic resistant bacteria mean?
    • What is a bacterial spore?
    • What is meant by vegetative state?
    • How does not taking the full course of an antibiotic lead to antibiotic resistant bacteria?
    • How does an entire strain of bacteria become antibiotic resistant?
  • Continue reading through the 'Examples of Antibiotic Resistant Bacteria' section, then ask and discuss:
    • What does MRSA stand for?
    • Which antibiotics are they resistant to?
    • Which antibiotic are VRE resistant to?
    • What is the name of the antibiotic resistant strain of TB bacteria?
  • Read the 'Lesson Summary' to your students and emphasize the main points.

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