Chain of Infection Lesson Plan

Instructor: Kerry Gray

Kerry has been a teacher and an administrator for more than twenty years. She has a Master of Education degree.

Teachers may use this lesson plan to teach students about the chain of infection. Students will summarize the stages in the chain of infection, provide examples, and discuss methods of preventing the spread of disease.

Learning Objectives

After completing this lesson, students will be able to:

  • Define and understand the chain of infection
  • Summarize the spread of disease and methods of prevention at each stage of the chain of infection


60 minutes

Curriculum Standards

  • NGSS.HS-LS1-2.

Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.


Determine the central ideas or conclusions of a text; summarize complex concepts, processes, or information presented in a text by paraphrasing them in simpler but still accurate terms.


Determine the meaning of symbols, key terms, and other domain-specific words and phrases as they are used in a specific scientific or technical context relevant to grades 11-12 texts and topics.


  • chain of infection
  • host
  • pathogen
  • portal
  • reservoir
  • transmission

Video & Discussion

  • Introduce the video: Chain of Infection: Definition & Example
  • Watch the 'Definition: The Chain of Infection' portion of the video. Pause at 0:39 to ask the following question:
    • What is the chain of infection?
  • Continue watching 'The Six Links' section of the video. Pause at 2:42 to discuss the following:
    • Name and describe each of the links in the chain of infection.
  • Watch the 'Example of a Chain of Infection' and 'Control Measures' portions of video. Pause at 3:36.
  • Have students name examples and methods to prevent the spread of disease at each stage of the chain of infection.
  • Watch the remainder of the video.
  • Pass out the printable worksheet
  • Have students complete the worksheet independently to check for understanding. Grade as a class and discuss answers.

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