Smallpox Lesson Plan

Instructor: Kandi Young

Kandi has degrees in Communications, Human Services, Education and Computer Science. She is a Business, Marketing, and Technology instructor with a Master's degree in Education.

This lesson focuses on examining the structure and replication of smallpox. This lesson provides strong emphasis on the replication processes of smallpox. The lesson provides several activities to engage all learning styles.

Learning Objectives

Students will be able to:

  • Explain what smallpox is
  • Describe the structure of smallpox
  • Understand how smallpox replicates

Length of Lesson

1-2 hours



Determine the central ideas or information of a primary or secondary source; provide an accurate summary of the source distinct from prior knowledge or opinions.


Integrate visual information (e.g., in charts, graphs, photographs, videos, or maps) with other information in print and digital texts.


  • Smallpox
  • Variola Virus
  • Envelope
  • Core
  • Intracellular mature virus (IMV)
  • Intracellular enveloped viruses (IEVs)
  • Cell-associated enveloped viruses (CEV)
  • External enveloped virus (EEV)
  • Endocytosis


  • Begin class with some prompt questions for a group discussion, such as:
    • How many of you have had a vaccine?
    • What do you think vaccines do?
    • What are some vaccines you have had?
  • Explain that smallpox has been eradicated because of vaccines.
  • Pass out the Smallpox Virus: Structure and Functionworksheet.
  • Ask students to complete the worksheet as they read the Smallpox Virus: Structure and Function lesson.
  • Have students share their answers to the worksheet and discuss the following points:
    • What are the symptoms of smallpox?
    • How does smallpox replicate?
    • How dangerous was smallpox?
    • Does the virus still exist today?
  • Have students complete the Smallpox Virus: Structure and Function quiz.

To unlock this lesson you must be a Member.
Create your account

Register to view this lesson

Are you a student or a teacher?

Unlock Your Education

See for yourself why 30 million people use

Become a member and start learning now.
Become a Member  Back
What teachers are saying about
Try it risk-free for 30 days

Earning College Credit

Did you know… We have over 200 college courses that prepare you to earn credit by exam that is accepted by over 1,500 colleges and universities. You can test out of the first two years of college and save thousands off your degree. Anyone can earn credit-by-exam regardless of age or education level.

To learn more, visit our Earning Credit Page

Transferring credit to the school of your choice

Not sure what college you want to attend yet? has thousands of articles about every imaginable degree, area of study and career path that can help you find the school that's right for you.

Create an account to start this course today
Try it risk-free for 30 days!
Create an account