Clinical Significance vs. Statistical Significance


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Dr. Smith is designing an experiment to test whether a new drug is effective at easing anxiety. He finds that his results are significant at a p-value of .05. What does this mean?

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1. A researcher is trying to figure out if a new therapy helps children with ADHD perform better in school. In order to run this experiment she will need a _____ of the _____ of children who have ADHD and attend school.

2. Dr. Martin conducted an experiment to test whether a new therapeutic intervention was better than existing ones and he found a p-value of .05 after conducting experiments but it does not seem like clinicians are using his new technique. This could be due to the fact that _____

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About This Quiz & Worksheet

How does clinical significance differ from statistical significance? Test your knowledge of these differences as well as different statistical terms by using the quiz/worksheet combo. Some questions will feature scenarios that include p-value and ADHD.

Quiz & Worksheet Goals

Using these materials helps you check your understanding of:

  • What a researcher needs to perform an experiment
  • The meaning of clinical significance
  • What statistical significance is
  • Types of samples
  • P-values

Skills Practiced

  • Information recall - access the knowledge you have gained about the meaning of a p-value
  • Interpreting information - verify that you can read information about what an experiment needs and interpret it correctly
  • Distinguishing differences - compare and contrast main topics, such as clinical significance and statistical significance

Additional Learning

Review more about these statistical topics by going through the lesson named Clinical Significance vs. Statistical Significance. These topics can also be reviewed:

  • What statistical significance is used for
  • Finding the p-value
  • Characteristics of different types of samples