Causes of Mutation and DNA Damage- Mutagens


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question 1 of 3

Which type of mutagen actually changes the chemical structure of certain nucleotides, causing them to mispair?

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1. How can base analogs cause mutations?


The mutagen 2-aminopurine looks like adenine (A) but can shape-shift to look more like guanine (G).

Deduce the class of mutagen involved in the above and the base pair change that could take place after a few rounds of DNA replication?

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About This Quiz & Worksheet

This quiz examines mutations and their causes, including chemical mutagens. Practice questions will test your ability to distinguish between three types of chemical mutagens.

Quiz & Worksheet Goals

In these assessments, you'll be tested over your ability to:

  • Identify the type of mutagen that changes the chemical structure of nucleotides
  • Identify the type of mutagen that often causes frameshift mutations
  • Name the class or type of a mutagen based on its characteristics and functions
  • Understand how base analogs cause mutations

Skills Practiced

This quiz and worksheet can help you develop the following skills:

  • Reading comprehension - ensure that you draw the most important information from the related lesson on mutagens
  • Making connections - use understanding of the concept of mutation
  • Defining key concepts - ensure that you can accurately define main phrases, such as base analog, base-modifying agents, and intercalating agents
  • Knowledge application - use your knowledge to answer questions about causes and types of chemical mutagens

Additional Learning

To learn more about mutations, review the accompanying lesson on mutagens as a cause of mutations. This lesson will cover the following objectives:

  • Define mutation and know the causes of it
  • Understand chemical mutations
  • Distinguish between base-analogs, base-modifying agents, and intercalating agents
  • Understand how the three above-named mutagens work