About This Chapter
Below is a sample breakdown of the Aberrant Immune System chapter into a 5-day school week. Based on the pace of your course, you may need to adapt the lesson plan to fit your needs.
|Day||Topics||Key Terms and Concepts Covered|
|Monday|| Inflammation overview;|
|Definition, causes and symptoms of inflammation;|
Causes and effects of inflammation
|Tuesday|| Chronic inflammation;|
Inflammation's impact on the body
|Causes of long-term inflammation and consequences;|
Systemic inflammatory responses including fever and cachexia
|Wednesday|| Treatments for inflammation;|
Type I hypersensitivity
|Drugs that treat inflammation, their pros and cons;|
Allergic reactions, IgE, mast cells, histamine
|Thursday|| Type II hypersensitivity;|
Type III hypersensitivity
|Definition of cytotoxicity, autoimmune hemolytic anemia, myasthenia grave;|
Immune complex hypersensitivity, glomerulonephritis, vasculitis
|Friday|| Type IV hypersensitivity;|
Autoimmune diseases and hypersensitivity
|Examples of delayed-type hypersensitivity, such as multiple sclerosis, CD4+ T cells, CD8+ T cells;|
Autoimmune disease, autoantibodies, hypersensitivity reaction
1. What Is Inflammation? - Definition, Causes & Symptoms
This lesson will cover the process of inflammation and what your body might do after a bee sting. We'll find out the five cardinal signs of inflammation as well as anaphylactic shock, histamine and cytokines in the process.
2. Acute Inflammation: Causes, Examples & Impact
This lesson teaches you about what occurs during acute inflammation. We'll discuss the causes and impacts of inflammation and learn terms like arachidonic acid, prostaglandins, leukotrienes, and eicosanoids.
3. Chronic Inflammation: Long Term Consequences
This lesson explores the harmful effects of long-term inflammation. We'll define chronic inflammation, inflammatory mediators, and reactive oxygen species before covering some specific causes of chronic inflammation and its consequences.
4. The Inflammatory Response's Effect on the Entire Body
This lesson will discuss two important roles systemic inflammation is involved in: fever and leukocytosis. It will also discuss the flip-side, two bad components of systemic inflammation: cachexia and anaphylactic shock.
5. Major Treatment Options for Inflammation
This lesson will discuss two major classes of drugs involved in suppressing the immune system: steroids and NSAIDs. We will discuss what they do, how they stop inflammation, and what side effects they may have.
6. Type I Hypersensitivity: Allergic Reactions
This lesson delves into something known as type I hypersensitivity reactions. You'll find out how everything from mast cells, basophils, and IgE to histamine, bee stings, and peanut allergies all play a role in this process.
7. Type II Hypersensitivity: Cytotoxic Hypersensitivity
This lesson will discuss something known as a type II hypersensitivity reaction. We will go over the principal mechanisms by which it occurs as well as the major antibodies involved. In addition, we'll cover autoimmune hemolytic anemia and myasthenia gravis.
8. Type III Hypersensitivity: Immune Complex Hypersensitivity
This lesson will discuss what a type III hypersensitivity reaction causes. It will delve into which antibodies are involved, the creation of immune complexes, the development of arthritis, vasculitis, and glomerulonephritis, and much more.
9. Type IV Hypersensitivity: Delayed-Type Hypersensitivity
This lesson will cover type IV hypersensitivity. We'll discuss the basics of how and why it occurs, the cells involved, and the most common types of diseases and conditions that are associated with this hypersensitivity reaction.
10. Autoimmune Diseases and Hypersensitivity
This lesson will talk about what defines an autoimmune disease, a hypersensitivity reaction, and more. We'll also discuss Graves' disease and myasthenia gravis.
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