About This Chapter
Control of Gene Expression - Chapter Summary
With this chapter, you're welcome to study control of gene expression any time that works best for you. Topics outlined here include regulation of gene expression, the transcription factor and RNA processing in eukaryotic cellS. You can access these resources on any smartphone, tablet or computer for a completely flexible and convenient study experience. If you get stuck on any of these concepts, reach out to an expert through the Dashboard with your questions. After finishing this chapter, you should be able to:
- Outline transcriptional repression and induction in the regulation of gene expression
- Explain how an operon controls transcription in a prokaryotic cell
- Define the transcription factor and its identification
- Provide examples of eukaryotic transcription regulation
- Identify the splicing of introns and exons in RNA processing in eukaryotic cells
- Give the definition and processes of RNA editing
- Discuss how siRNA molecules inhibit mRNAs
- Detail the role, steps and structure of MicroRNAs (miRNAs)
1. Regulation of Gene Expression: Transcriptional Repression and Induction
Do our genes work the same way all the time? How do we regulate the expression of our genes? Explore the various ways organisms control gene transcription through repression and induction of operons.
2. How An Operon Controls Transcription in a Prokaryotic Cell
Is gene regulation really as simple as flipping a switch? What are the parts of an operon, and how do they function to control gene transcription? We'll study the lac operon to answer these questions.
3. Transcription Factor: Definition & Identification
What is a transcription factor? Transcription factors are one of several ways cells regulate genetic expression. In this lesson we will cover how transcription factors were first identified and how they function.
4. Examples of Transcription Regulation in Eukaryotes
Transcription is more complicated than just turning a gene 'on' or 'off' like a light switch. In this lesson, you'll learn how eukaryotic transcription is regulated through the use of DNA regulatory regions, DNA methylation, and chromatin modification.
5. RNA Processing in a Eukaryotic Cell: Splicing of Introns & Exons
In this lesson, we'll explore the unique considerations for gene regulation in the eukaryotic cell. We'll walk through RNA splicing of introns and exons and the addition of the 5' cap and poly(A) tail.
6. RNA Editing: Definition & Processes
In this lesson, we'll be learning about RNA editing. We'll explain what RNA editing is and look at different mechanisms, such as addition, deletion, and substitution through deamination and chemical alternation.
7. RNAi: How siRNA Molecules Inhibit mRNAs
In this lesson, you will learn how siRNA helps cells fight viruses and controls gene expression and how scientists are using siRNA to understand genetic diseases and develop new therapies.
8. MicroRNAs (miRNAs): Role, Structure & Steps
In this lesson, we'll be exploring the world of microRNAs (miRNAs). Here, we'll explain the role of miRNAs, their structure and the steps needed to control gene expression.
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Other chapters within the Biology 203: Cell & Molecular Biology course
- Biological Molecules
- Cell Structure & Function Overview
- Cell Membrane & Transport Overview
- Principles of Cell Metabolism
- Photosynthesis Fundamentals
- Cellular Respiration & Fermentation
- Cell Cycles
- Patterns of Genetic Inheritance
- DNA Structure & Replication
- Mutation & DNA Damage
- The Central Dogma of Biology & Protein Synthesis
- Structure & Function of Viruses
- Genetic Manipulation Overview