About This Chapter
Below is a sample breakdown of the DNA Replication chapter into a 5-day school week. Based on the pace of your course, you may need to adapt the lesson plan to fit your needs.
|Day||Topics||Key Terms and Concepts Covered|
|Monday||Definition of DNA replication||Conservative, semi-conservation and dispersive models, experiments of Matthew Meselson and Franklin Stahl|
|Tuesday||The function of helicase||How the DNA double helix is unwound prior to replication, DNA helicase, replication fork, origin of replication|
|Wednesday||How replication is initiated||DNA polymerase, RNA primase|
|Thursday||How replication is completed||Reiji Okazaki's work, leading strand, lagging strand, DNA ligase|
|Friday||Overview of the DNA replication process||enzymes, replication bubbles, leading and lagging strands|
1. What Is DNA Replication? - Conservative, Semi-Conservative & Dispersive Models
How do we know that DNA replication is semi-conservative? How do we know it's not conservative or dispersive? Let's follow the famous experiment by Meselson and Stahl to find out!
2. DNA Replication Lesson Plan & Activity
What happens during DNA replication? A video lesson provides detailed information and an activity allows students to create a simple model. Related lessons and additional activities will help you take instruction further.
3. DNA Replication Activities & Games
DNA can be a complex topic, but these hands-on, fun activities and games can make it easier to understand. They can also serve as an excellent jumping-off point for more complex biological topics.
4. How Helicase Unwinds the DNA Double Helix in Preparation for Replication
How does semi-conservative replication begin? Discover how DNA helicase creates a replication fork to unwind the complicated DNA molecule and allow daughter strands to form on the parental template.
5. How DNA Polymerase and RNA Primase Initiate DNA Replication
How do enzymes assist in starting DNA replication? In this lesson, we explore the work of a contributing enzyme, DNA polymerase, and learn how the RNA primer is made by the action of RNA primase.
6. DNA Replication: The Leading Strand and DNA Polymerase Activities
How does replication occur in the antiparallel DNA molecule? In this lesson, explore the significance of the leading and lagging strands, and learn how Okazaki fragments and RNA ligase make DNA replication possible.
7. DNA Replication: Review of Enzymes, Replication Bubbles & Leading and Lagging Strands
Feeling lost in the thorny details of DNA replication? This lesson provides an overview of semi-conservative replication, with a focus on putting together all of the concepts involved. We'll review the work of each enzyme on our way to completing the big picture of DNA replication.
8. Enzyme Lesson Plan
This lesson provides a broad introduction to enzymes, substrates and the energy of activation. A video, discussions, demonstrations and lab activities help to engage and instruct students.
9. Enzyme Inhibition Lesson Plan
Enzymes are an integral part of many cellular processes in our bodies. Your students will learn about enzyme inhibition as they watch and discuss a video lesson, create enzyme inhibition cards and take a short quiz.
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