About This Chapter
Below is a sample breakdown of the DNA Replication: Processes and Steps chapter into a 5-day school week. Based on the pace of your course, you may need to adapt the lesson plan to fit your needs.
|Day||Topics||Key Terms and Concepts Covered|
|Monday||What is DNA Replication?||Description of the conservative, dispersive and semi-conservative models associated with DNA replication|
|Tuesday||Role of the DNA Helicase in Replication||Division of nucleic acid strands, enzymatic function of the DNA helicase, origin of replication and shape of the replication fork|
|Wednesday||Role of DNA Polymerase and RNA Primase in Replication||Explanation of how DNA polymerase and RNA primase begin the replication process; description of the zipper model|
|Thursday||The Leading Strand and DNA Polymerase Activities||Importance of DNA polymerase as an enzyme, differences between leading and lagging strands and roles of RNA ligase and Okazaki fragments in DNA replication|
|Friday||Summary of DNA Replication: Semi-Conservative Replication||Review of the key enzymes found in the DNA replication process, leading and lagging strands and replication bubbles|
1. What Is DNA Replication? - Conservative, Semi-Conservative & Dispersive Models
How do we know that DNA replication is semi-conservative? How do we know it's not conservative or dispersive? Let's follow the famous experiment by Meselson and Stahl to find out!
2. How Helicase Unwinds the DNA Double Helix in Preparation for Replication
How does semi-conservative replication begin? Discover how DNA helicase creates a replication fork to unwind the complicated DNA molecule and allow daughter strands to form on the parental template.
3. How DNA Polymerase and RNA Primase Initiate DNA Replication
How do enzymes assist in starting DNA replication? In this lesson, we explore the work of a contributing enzyme, DNA polymerase, and learn how the RNA primer is made by the action of RNA primase.
4. DNA Replication: Review of Enzymes, Replication Bubbles & Leading and Lagging Strands
Feeling lost in the thorny details of DNA replication? This lesson provides an overview of semi-conservative replication, with a focus on putting together all of the concepts involved. We'll review the work of each enzyme on our way to completing the big picture of DNA replication.
5. DNA Replication: The Leading Strand and DNA Polymerase Activities
How does replication occur in the antiparallel DNA molecule? In this lesson, explore the significance of the leading and lagging strands, and learn how Okazaki fragments and RNA ligase make DNA replication possible.
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