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- Effects on DNA of point mutations, insertions and deletions
- Missense, nonsense and silent mutations
- Effects of frameshift mutations
1. What is a Point Mutation? - Definition, Causes & Types
Point mutations are changes to the genetic sequence where a single nucleotide base is changed, inserted, or deleted. Explore the definition and causes of point mutations and discover the difference between the two basic types: base substitutions and insertion and deletion.
2. Effects of Mutations on Protein Function: Missense, Nonsense, and Silent Mutations
Proteins are vital for healthy cells, and protein function can be negatively affected by point mutations. Learn about missense, nonsense, and silent mutations and understand the effects mutations have on the function of proteins.
3. Mutagens: How the Environment Affects Mutation Rates
Mutations are caused by environmental agents called mutagens. Explore how mutations are formed, the role of DNA polymerase in preventing mutations, and how mutations affect the real world.
4. Effects of Frameshift Mutations: Definitions and Examples
Frameshift mutations happen when a protein is drastically changed because of an insertion or a deletion. Review the different types of mutations, the codon reading frame, and how damaging frameshift mutations really are.
5. Missense Mutation: Definition & Example
While people with sickle-cell disease show many symptoms, such as pain and fatigue, this disease is caused by only a single change in a DNA sequence. You can learn more about this kind of change, called a missense mutation, in this lesson.
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