About This Chapter
The Consequences of an Aberrant Immune System - Chapter Summary and Learning Objectives
Understand how inflammation occurs in and affects the body with this chapter's lessons on the aberrant immune system. Instructors cover various types of inflammation and how it manifests, as well as the effects it can have if left unchecked. You'll also receive information about different levels of hypersensitivity reactions and examples of diseases within each. The lessons of this chapter are formulated to help you:
- Understand the effects, types, symptoms, and causes of inflammation
- Grasp the implications of long-term inflammation in the body
- Discuss potential treatments for different types of inflammation
- Recognize the range of hypersensitivity responses and related antibodies
|What Is Inflammation? - Definition, Causes, and Symptoms||Learn the five fundamental indicators of inflammation and how the body responds to it. Define histamine, anaphylactic shock, and cytokines.|
|Acute Inflammation: Causes, Examples, and Impact||Understand how inflammation impacts the vascular system locally and systematically. Identify the body's chief inflammatory mediators.|
|Chronic Inflammation: Long-Term Consequences||Articulate causes of long-term inflammation and relevant inflammatory mediators. Recognize the potential outcomes of ongoing inflammation.|
|The Inflammatory Response's Effect on the Entire Body||Understand inflammation's relationship to pain, fever, and the immune system. Explain anaphylactic shock.|
|Major Treatment Options for Inflammation||Identify inflammation drug treatments and correlative risks or side effects.|
|Confounding Factors of Inflammation||Explain how different diseases or lifestyle factors may affect inflammation.|
|Type I Hypersensitivity: Allergic Reactions||Learn how allergic reactions take place in and affect the body.|
|Type II Hypersensitivity: Cytotoxic Hypersensitivity||Understand how cytotoxic hypersensitivity reactions occur in the body. Identify involved antibodies.|
|Type III Hypersensitivity: Immune Complex Hypersensitivity||Learn about hypersensitivity III responses and related antibodies. Understand how issues such as vasculitis, arthritis, etc., arise.|
|Type IV Hypersensitivity: Delayed-Type Hypersensitivity||Recognize the causes and most common manifestations of type IV hypersensitivity. Understand the cell types involved.|
|Autoimmune Diseases and Hypersensitivity||Articulate the relationship between autoimmune disease and hypersensitivity. Identify types of autoimmune diseases.|
1. What Is Inflammation? - Definition, Causes & Symptoms
When the body is attacked by something it deems harmful, a response called inflammation often occurs. Learn the definition of inflammation, its causes, symptoms, and its relationship to the immune system, and examine its components and influences in the body, the relationship between histamine and cytokines, and the short- and long-term consequences that can result from inflammation.
2. Acute Inflammation: Causes, Examples & Impact
Acute inflammation can have many causes. Understand how the body reacts to harmful stimulus and its impact, learn what can cause inflammation, examine arachidonic acid, and explore examples and other mediators of inflammation.
3. Chronic Inflammation: Long Term Consequences
Chronic inflammation harms the human body though the extended release of mediators that directly or indirectly do it damage. Learn about it though a definition, identify some of its causes, and understand some of its long term consequences.
4. The Inflammatory Response's Effect on the Entire Body
Inflammatory responses in the body can have an impact on the entire body. Understand the effects of inflammation if it is not kept in check and learn the definitions of pyrexia, leukocytosis, cachexia, and anaphylactic shock.
5. Major Treatment Options for Inflammation
Inflammation is the immune system's response that, if continuous, causes pain, fever, and damage to body tissue. Learn the function and side effects of drugs that combat inflammation such as steroids or NSAIDs, and examples of other pharmacological inflammation-inhibitors.
6. Type I Hypersensitivity: Allergic Reactions
A type I hypersensitivity reaction occurs when the immune system produces an overabundance of IgE antibodies to counteract an allergen. Learn more about the pathophysiology of type I hypersensitivity and discover how it relates to anaphylactic shock.
7. Type II Hypersensitivity: Cytotoxic Hypersensitivity
Type II hypersensitivity is an antibody-mediated immune reaction that can result in impairment or destruction of bodily tissues. Learn about type II and cytotoxic hypersensitivities, how destruction occurs by connections in the body, and how type II hypersensitivity reactions cause disease.
8. Type III Hypersensitivity: Immune Complex Hypersensitivity
Type III hypersensitivity, or immune complex hypersensitivity, is when antibodies form aggregates of antibodies and antigens called immune complexes. Discover type III hypersensitivity reactions and how they can cause vasculitis, arthritis, and glomerulonephritis in this lesson.
9. Type IV Hypersensitivity: Delayed-Type Hypersensitivity
Humans can experience significant inflammatory reactions from delayed antigen responses caused by type IV hypersensitivity, also dubbed delayed-type hypersensitivity. Learn about type IV hypersensitivity, why T lymphocytes are dangerous to healthy cells and find examples of reactions and diseases.
10. Autoimmune Diseases and Hypersensitivity
Autoimmune diseases occur when the immune system attacks the body's cells or receptors. Explore the friendly fire that creates autoimmune diseases and hypersensitivity reactions, and then discover the different types of autoimmune diseases.
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Other chapters within the Pathophysiology Textbook course
- The Basic Components of Pathophysiology
- The Pathophysiology of Neoplasia
- Skin Related Pathology
- Trauma and Injury to the Nervous System
- Major Disorders Involving the Nervous System
- Congenital Cardiovascular Defects
- Acquired Cardiovascular Abnormalities
- Pathologies of the Respiratory System
- Important Renal Anatomy and Physiology
- Diseases of the Urinary System
- Conditions Affecting the Gastrointestinal System
- Metabolic Derangements
- Blood Disorders: Anemia
- Hematological Maladies
- Blood Cancers
- Alterations of the Musculoskeletal System
- Reproductive System Disorders
- Clinical Test Results: Electrolytes, Cells, and Blood Proteins
- Clinical Test Results: Organ Function and Health