About This Chapter
The Consequences of an Aberrant Immune System - Chapter Summary and Learning Objectives
Understand how inflammation occurs in and affects the body with this chapter's lessons on the aberrant immune system. Instructors cover various types of inflammation and how it manifests, as well as the effects it can have if left unchecked. You'll also receive information about different levels of hypersensitivity reactions and examples of diseases within each. The lessons of this chapter are formulated to help you:
- Understand the effects, types, symptoms, and causes of inflammation
- Grasp the implications of long-term inflammation in the body
- Discuss potential treatments for different types of inflammation
- Recognize the range of hypersensitivity responses and related antibodies
|What Is Inflammation? - Definition, Causes, and Symptoms||Learn the five fundamental indicators of inflammation and how the body responds to it. Define histamine, anaphylactic shock, and cytokines.|
|Acute Inflammation: Causes, Examples, and Impact||Understand how inflammation impacts the vascular system locally and systematically. Identify the body's chief inflammatory mediators.|
|Chronic Inflammation: Long-Term Consequences||Articulate causes of long-term inflammation and relevant inflammatory mediators. Recognize the potential outcomes of ongoing inflammation.|
|The Inflammatory Response's Effect on the Entire Body||Understand inflammation's relationship to pain, fever, and the immune system. Explain anaphylactic shock.|
|Major Treatment Options for Inflammation||Identify inflammation drug treatments and correlative risks or side effects.|
|Confounding Factors of Inflammation||Explain how different diseases or lifestyle factors may affect inflammation.|
|Type I Hypersensitivity: Allergic Reactions||Learn how allergic reactions take place in and affect the body.|
|Type II Hypersensitivity: Cytotoxic Hypersensitivity||Understand how cytotoxic hypersensitivity reactions occur in the body. Identify involved antibodies.|
|Type III Hypersensitivity: Immune Complex Hypersensitivity||Learn about hypersensitivity III responses and related antibodies. Understand how issues such as vasculitis, arthritis, etc., arise.|
|Type IV Hypersensitivity: Delayed-Type Hypersensitivity||Recognize the causes and most common manifestations of type IV hypersensitivity. Understand the cell types involved.|
|Autoimmune Diseases and Hypersensitivity||Articulate the relationship between autoimmune disease and hypersensitivity. Identify types of autoimmune diseases.|
1. What Is Inflammation? - Definition, Causes & Symptoms
This lesson will cover the process of inflammation and what your body might do after a bee sting. We'll find out the five cardinal signs of inflammation as well as anaphylactic shock, histamine and cytokines in the process.
2. Acute Inflammation: Causes, Examples & Impact
This lesson teaches you about what occurs during acute inflammation. We'll discuss the causes and impacts of inflammation and learn terms like arachidonic acid, prostaglandins, leukotrienes, and eicosanoids.
3. Chronic Inflammation: Long Term Consequences
This lesson explores the harmful effects of long-term inflammation. We'll define chronic inflammation, inflammatory mediators, and reactive oxygen species before covering some specific causes of chronic inflammation and its consequences.
4. The Inflammatory Response's Effect on the Entire Body
This lesson will discuss two important roles systemic inflammation is involved in: fever and leukocytosis. It will also discuss the flip-side, two bad components of systemic inflammation: cachexia and anaphylactic shock.
5. Major Treatment Options for Inflammation
This lesson will discuss two major classes of drugs involved in suppressing the immune system: steroids and NSAIDs. We will discuss what they do, how they stop inflammation, and what side effects they may have.
6. Type I Hypersensitivity: Allergic Reactions
This lesson delves into something known as type I hypersensitivity reactions. You'll find out how everything from mast cells, basophils, and IgE to histamine, bee stings, and peanut allergies all play a role in this process.
7. Type II Hypersensitivity: Cytotoxic Hypersensitivity
This lesson will discuss something known as a type II hypersensitivity reaction. We will go over the principal mechanisms by which it occurs as well as the major antibodies involved. In addition, we'll cover autoimmune hemolytic anemia and myasthenia gravis.
8. Type III Hypersensitivity: Immune Complex Hypersensitivity
This lesson will discuss what a type III hypersensitivity reaction causes. It will delve into which antibodies are involved, the creation of immune complexes, the development of arthritis, vasculitis, and glomerulonephritis, and much more.
9. Type IV Hypersensitivity: Delayed-Type Hypersensitivity
This lesson will cover type IV hypersensitivity. We'll discuss the basics of how and why it occurs, the cells involved, and the most common types of diseases and conditions that are associated with this hypersensitivity reaction.
10. Autoimmune Diseases and Hypersensitivity
This lesson will talk about what defines an autoimmune disease, a hypersensitivity reaction, and more. We'll also discuss Graves' disease and myasthenia gravis.
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Other chapters within the Pathophysiology Textbook course
- The Basic Components of Pathophysiology
- The Pathophysiology of Neoplasia
- Skin Related Pathology
- Trauma and Injury to the Nervous System
- Major Disorders Involving the Nervous System
- Congenital Cardiovascular Defects
- Acquired Cardiovascular Abnormalities
- Pathologies of the Respiratory System
- Important Renal Anatomy and Physiology
- Diseases of the Urinary System
- Conditions Affecting the Gastrointestinal System
- Metabolic Derangements
- Blood Disorders: Anemia
- Hematological Maladies
- Blood Cancers
- Alterations of the Musculoskeletal System
- Reproductive System Disorders
- Clinical Test Results: Electrolytes, Cells, and Blood Proteins
- Clinical Test Results: Organ Function and Health