About This Chapter
Below is a sample breakdown of the Pathophysiology of Neoplasia chapter into a 5-day school week. Based on the pace of your course, you may need to adapt the lesson plan to fit your needs.
|Day||Topics||Key Terms and Concepts Covered|
|Monday||Neoplasia basics and causes of cancer||Benign, in situ, oncology, malignant, initiation, promotion, progression, radiation, toxins, asbestos, genes, smoking and chronic inflammation|
|Tuesday||Cancer syndromes, genetic risk factors and cancer at the genome level||Genetic syndromes, oncogenesis and viral oncogenesis|
|Wednesday||Tumor suppressor genes and benign vs. malignant||Retinoblastoma features, genetic cause, encapsulation, mitotic index, visual changes, metastasis, microscopic and macroscopic changes|
|Thursday||Metastasis, cancer progression and tumor markers||Staging, grading, diagnosis, primary vs. secondary growth, tissue function impairment, differentiation, tools used for diagnoses and indications of tumor markers|
|Friday||Cancer's basic pathophysiology, general treatment strategies and thyroid cancer example||Paraneoplastics syndrome, thrombosis, organ dysfunction, compression, surgery, radiation and chemotherapy|
1. What is Neoplasia? - Definition, Types & Examples
This lesson will discuss the concept of neoplasia. We'll specifically talk about the differences between benign tumors, carcinoma in situ, and malignant tumors. This lesson will also define metastasis and oncology and show examples of different types of malignant and benign tumors.
2. What Causes Cancer?
This lesson will discuss a model of cancer formation as well as some things that can cause cancer. You'll learn about initiation, promotion, and progression as well as what occurs during each step.
3. Cancer Syndromes & Genetic Risk Factors for Cancer
This lesson describes something called cancer syndrome or family cancer syndrome, as well as the important clues that can help it be detected and two examples of such a condition.
4. Cancer at the Level of the Genome
This lesson will delve into the genetic changes that may occur during cancer formation. You'll learn about proto-oncogenes, oncogenes, tumor suppressor genes, viral oncogenesis, p53, and more.
5. Tumor Suppressor Genes: Retinoblastoma Features, Genetic Cause & Treatment
In this lesson, you'll learn about retinoblastoma, which is a rare childhood cancer of the retina. Retinoblastoma is often inherited in an autosomal dominant fashion. Find out why retinoblastoma and other types of hereditary cancers are caused by dominant alleles by watching this lesson.
6. Benign vs. Malignant: Definition, Characteristics & Differences
This lesson will talk about the common distinctions between malignant and benign tumors. We'll discuss how they may look or feel and how it is that they may look differently under the microscope as well.
7. Metastasis: How Cancer Spreads
This lesson will describe the concept of cancer spreading around the body, or metastasis, as well as why it may occur, how it occurs, why it may fail, and how your blood vessels play a critical role in this process.
8. The Progression of Cancer: Grading, Staging & Diagnosis
This lesson will discuss the way by which cancer is diagnosed, graded, and staged. We'll talk about what staging and grading actually mean and how and why cancers may be high or low in grade.
9. What Are Tumor Markers? - Definition & Functions
This lesson will discuss the concept of tumor markers. You'll learn what they are, where they are found, and what they are used for. We'll also go into three specific and famous tumors markers known as PSA, CEA, and AFP.
10. The General Pathophysiology of Cancer
This lesson seeks to tell you about how cancer impacts the body in a wide variety of ways both directly and indirectly. We'll discuss things like pressure atrophy, paraneoplastic syndromes, peritonitis, and many other things.
11. The General Treatment Strategies For Cancer
This lesson will describe the three traditional methods of treating cancer. These include surgery, radiation therapy, and chemotherapy as well as their potential uses, benefits, and side-effects. We'll also touch on other ways by which we can treat cancer.
12. Thyroid Cancer: An Example of Malignant Neoplasia
This lesson will describe the composition and function of the thyroid gland. We'll go into which hormones it produces, what they do, and how they may play a role in thyroid cancer. We'll also discuss the diagnosis and treatment of thyroid cancer.
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Other chapters within the Pathophysiology Syllabus Resource & Lesson Plans course
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