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Major Blood Vessels That Carry Blood Away From the Heart

Betsy Chesnutt, Rebecca Gillaspy
  • Author
    Betsy Chesnutt

    Betsy has a Ph.D. in biomedical engineering from the University of Memphis, M.S. from the University of Virginia, and B.S. from Mississippi State University. She has over 10 years of experience developing STEM curriculum and teaching physics, engineering, and biology.

  • Instructor
    Rebecca Gillaspy

    Dr. Gillaspy has taught health science at University of Phoenix and Ashford University and has a degree from Palmer College of Chiropractic.

Discover how blood is carried away from the heart, and learn which blood vessels carry blood to and from the heart. Understand the difference between arteries, veins, and vessels. Updated: 11/21/2023
Frequently Asked Questions

What are the two main blood vessels that carry blood to the heart?

The two main blood vessels that carry blood to the heart are the pulmonary vein, which carries oxygenated blood from the lungs back to the heart, and the vena cava, which carries deoxygenated blood from the tissues back to the heart.

Which blood vessels carry blood to and from the lungs?

The pulmonary artery carries deoxygenated blood to the lungs, and the pulmonary vein carries oxygenated blood back to the heart.

Which are the two arteries that carry blood away from the heart?

The pulmonary artery carries deoxygenated blood to the lungs, and once it returns to the heart (via the pulmonary vein), oxygenated blood is pumped out to the rest of the body through the largest artery in the body, the aorta.

What blood vessels carry blood away the heart?

The blood vessels that carry blood away from the heart are known as arteries. Arteries usually carry oxygen-rich blood, but one artery, the pulmonary artery, carries deoxygenated blood from the heart to the lungs.

On average, it takes about a minute for blood to leave the heart, circulate throughout the body, and return to the heart to be pumped back out again. What carries all that blood throughout the entire body? There is a complex network of blood vessels that takes blood from the heart to the rest of the body. The blood vessels that carry blood away from the heart are known as arteries, while those that carry blood back to the heart are veins.

When blood first returns to the heart, it is very low in oxygen, so the first journey it makes is from the heart to the lungs, where it can pick up oxygen and get rid of carbon dioxide. The pulmonary artery is a large artery that carries this deoxygenated blood to the lungs. After passing through tiny capillaries in the lungs and becoming oxygenated, blood travels back to the left atrium of the heart via the pulmonary veins. The pulmonary arteries and veins are different from the rest of the circulatory system because the pulmonary artery is the only artery to carry deoxygenated blood, and the pulmonary vein is the only vein to carry blood that contains a lot of oxygen.

After returning from the lungs, freshly oxygenated blood enters the left atrium of the heart. From there, it flows into the left ventricle, and when the left ventricle contracts with each heartbeat, blood is pushed out of the heart and into the largest artery in the body, the aorta. The left ventricle is much thicker than the right ventricle because it has to generate much higher pressures in order to pump blood throughout the entire body.

The aorta is a very large artery with thick, muscular walls. It must be able to withstand high pressures and allow a tremendous amount of blood to pass through it without leaking. The aorta branches into several smaller arteries, and these keep branching and getting smaller and smaller until they reach capillaries, which are so tiny that they are only about the width of a single blood cell. This is where oxygen and carbon dioxide exchange can occur. Once blood leaves capillaries, it enters into the other side of the circulatory system, which is made up of veins that return the blood back to the heart.

Arteries (shown in red) carry blood away from the heart, while veins (shown in blue) return blood to the heart.

An image of the human circulatory system, showing the major arteries (in red) and veins (in blue).

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  • 0:06 Major Blood Vessels
  • 1:03 Aorta
  • 2:36 Coronary Arteries
  • 3:29 Aortic Arch
  • 3:56 Baroreceptors
  • 4:33 Lesson Summary

Once blood leaves the arterioles and travels through the capillaries, it gives up most of its oxygen and picks up carbon dioxide. Then, this deoxygenated blood enters the venous system, which returns blood back to the heart. It first enters tiny venules that join together into larger and larger veins, eventually delivering blood into the largest vein in the body, the vena cava, which carries deoxygenated blood back to the heart to begin the cycle all over again.

Arteries carry blood away from the heart, and veins bring blood back to the heart. The pulmonary artery carries deoxygenated blood from the right ventricle of the heart to the lungs, and the pulmonary veins carry oxygenated blood back to the heart. Then, the left ventricle pumps blood into the aorta, which is the largest artery in the body. Along with the pulmonary artery, the aorta is an elastic artery that contains a large amount of elastic tissue in its walls. This elastic tissue allows the aorta to stretch, and there are also baroreceptors that detect how much the aorta is stretching. This information is used by the nervous system to control blood pressure. Once blood leaves the aorta, it enters muscular arteries, which are relatively large arteries that contain some elastic tissue, as well as a large amount of smooth muscle tissue. Then, blood enters the smaller arterioles that transmit blood into capillaries.

Inside capillaries, gas exchange occurs, and deoxygenated blood then enters venules on the other side. These venules come together to form deep veins and superficial veins, which both have similar structures. These veins have thinner walls than arteries and also contain valves to prevent blood from flowing back away from the heart. Finally, veins carry blood into the vena cava, which is the largest vein in the body, and from there, it goes back into the right atrium of the heart so the process can start all over again!

Video Transcript

Major Blood Vessels

Like a system of roads, your circulatory system has its own large highways and smaller back roads. In this lesson, you will learn about the largest highway, or artery, in your body. Where this artery leaves your heart, it is, in fact, very large; it's about the size of a garden hose. It first rises upward from the left ventricle of your heart before making a U-turn and plunging downward, running deep inside your body and following close to your spinal column. Early in this large vessel's journey, it sends off branches that feed important organs and structures such as your heart, brain, head, neck and arms.

Before we formally introduce this major blood vessel leaving the heart, let's visit Mr. Smith's very busy widget factory. At the factory loading docks, we see Mr. Smith's truck drivers have loaded their trucks and are ready to deliver brand-new widgets to all of the stores around the country.

Aorta

Diagram of the aorta and ventricles of the heart
Aorta Ventricle Diagram

To do this in an efficient way, his drivers head out on the largest highway: Highway A. Your circulatory system also has a major highway, and it is called your aorta. This is the largest artery and carries blood from the heart to the body. Your body has miles and miles of arteries, and, as you can imagine, blood must come out of the heart under very high pressure. Blood is forced into the aorta from the left ventricle of your heart, and, because so much force is needed to propel blood all the way around your body, we notice that the left ventricle has a more muscular wall than the right ventricle, which has the comparatively smaller job of pumping blood the short distance to the nearby lungs. We already learned that the aorta is about the size of a garden hose, and this large size helps distribute some of the pressure. The aorta also contains many elastic fibers that allow it to expand when blood first enters and then relax as the blood moves along. This ability to stretch and relax makes the flow of blood smoother as it travels through your circulatory system.

Your aorta is one long, continuous tube with many branches that come off of the vessel like back roads would come off of a highway. As it courses through your body, your aorta is assigned different names along its path. The ascending aorta is the first section of the aorta and contains blood from the left ventricle of the heart.

Coronary Arteries

Blockages in the coronary arteries cause heart attacks
Coronary Artery Plaque

We don't have to travel far along the ascending aorta before reaching the first branching roads, and these are called your right and left coronary arteries. The coronary arteries are the arteries that supply blood to the heart muscle. You can imagine that the heart muscle is one of the most important muscles in your body, and therefore, your circulatory system wastes no time supplying it with richly oxygenated blood straight off of the aorta. An interesting fact about the coronary arteries is that they are relatively narrow, and these are the arteries that can become hardened and clogged due to buildup of plaque on their inner walls. If the blood flow through the coronary arteries is blocked, it can cause pain, and we call that angina. Or, if they're blocked more completely, it can result in a heart attack.

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